Dr. James Rodin, M.D has been in practice since 1981 and has worked at the Good Samaritan Hospital as Director of Men's Health Services for the past 10 years. The rest of this text is filler. Mutant type virus in Case 2 may have occurred because of immune pressure exerted by high titre anti-HBs detectable for more than 7 months. Cases 1 and 3 received only brief courses of anti-HBs therapy.